South Lowell Vacations from $429

Book a Hotel + Flight or Car together to unlock savings

Your South Lowell Vacation

Book a South Lowell vacation package and experience the rhythm and vibe of this vibrant neighborhood. With all your travel plans worked out, the only thing you need to concentrate on here is living your best life. Kick start your trip to South Lowell with a visit to nearby attractions such as University of Massachusetts Lowell, Tsongas Arena and Lowell Memorial Auditorium. Whatever your travel plans or the size of your budget, booking your perfect South Lowell vacation has never been easier with Expedia.

The Latest South Lowell Vacation Packages

Price found within the past 48 hours. Click for updated prices.
The Coonamessett
Boston Lodge and Suites
Boston Harbor Hotel
The Onset Beach Compound-Cape Cod Beach Resort & Oceanic Habitat
Encore Boston Harbor

Where to stay in South Lowell

Find the best South Lowell areas and neighborhoods for the activities you enjoy most. Learn more about South Lowell

South Lowell Hotel Deals

Sonesta Select Boston Lowell Chelmsford

Sonesta Select Boston Lowell Chelmsford

3 out of 5
30 Industrial Ave East Lowell MA
$98 nightly
The price is $110 total per night from Nov 15 to Nov 16
$110 total
Nov 15 - Nov 16
Total with taxes and fees
Sonesta Select Boston Lowell Chelmsford
Four Points by Sheraton Boston Newton

Four Points by Sheraton Boston Newton

3.5 out of 5
320 Washington Street Newton MA
Fully refundableReserve now, pay when you stay
$101 nightly
The price is $113 total per night from Dec 6 to Dec 7
$113 total
Dec 6 - Dec 7
Total with taxes and fees
8.4/10 Very Good! (2,668 reviews)
"Nice."

Reviewed on Nov 12, 2026

Four Points by Sheraton Boston Newton
Bedford Plaza Hotel - Boston

Bedford Plaza Hotel - Boston

3 out of 5
340 Great Road Bedford MA
Fully refundableReserve now, pay when you stay
$99 nightly
The price is $111 total per night from Nov 15 to Nov 16
$111 total
Nov 15 - Nov 16
Total with taxes and fees
6.6/10 (1,408 reviews)
"This hotel and their staff is below average for a 2 star hotel"

Reviewed on Nov 12, 2026

Bedford Plaza Hotel - Boston
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Stay near popular South Lowell attractions

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.